A new drug for weight loss and treatment of depression and addiction
Despite the reservations of many specialists and approved by the Food and Drug Administration on a new drug for weight loss called Ntrev It represents a combination of an antidepressant drug with an anti-drug addiction.
The approval came on the new drug by vote 13:7 surrounded by a concern of specialists because of the risk of increased blood pressure and the incidence of heart attack or stroke by ingestion of the drug at some of the members of the Advisory Board of the Food and Drug Administration had agreed earlier to the possibility of studying risk health of the drug after approval.
Although the opinion of the Advisory Board is binding on the management but they took it as published Ososhisd Press Agency this week.
Strangely enough, the Food and Drug Administration had rejected two other types of weight loss drugs in the month of October, but returned to agree to a property on the production.
The company has funded a study on the real estate newspaper published in the Lancet medical last July. The study found that drug ? Contrev helped people lose weight with diet and exercise.
Effectiveness of the drug
The study proved that people who took the drug for a year were able to decrease approximately 5% of their weight but the side effects of the drug made about half of the sample members stop participating in the study before completing one year of the drug.
He also told the researchers that the drug works to decrease the activation weight to change the work of the central nervous system in the body. ?
The sample was formed than 1,700 participants (15% of men and 85% of women) from across the United States between the ages of 18 and 65 years. ?
And all members of the sample suffering from obesity or overweight with an increase in fat with blood or an increase in blood pressure.
The researchers asked the respondents to reduce the amount of food they eat with the exercise of some physical exercise and then were divided into two groups and one dealt with a drug and the other components Areda?aa drug Contrev
? and after about 56 weeks completed only half of the sample (870 people) study, while others stop. It is proven that about half of individuals who completed the study (48%) of those given the drug succeeded in reducing their weight by 5%, while only 16% able to those who took the drug alternative to lose weight the same that amount.
Have suffered about 30% of the group that dealt with drug ? ? Contrev of some health problems such as nausea, headache, constipation, dizziness, vomiting and dry mouth.
And with that believed that researchers ? Contrev gives people who want to lose weight a new option ?.
However, the d. Lona Sandon, assistant professor of clinical nutrition at the University of Texas ? wondering about reasons for the decline of 50% of respondents for completion of the study and whether it was because of some side effects of the drug or the lack of slow weight did not live up to the expectations of the participants so they retracted in the middle of the road.
The author of the study published in a newspaper article in the Lancet expressed concern about the failure ? drug in reducing blood pressure significantly between the group that achieved the highest reduction in weight. This writer asked a professor of nutrition at the University of the article Copenhagen, Denmark Arne Ostrup to carry out further studies to gain access to better assess the risks of the drug on the blood vessels of the heart.
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